Hilty, M. P., Siebenmann, C., Rasmussen, P., Keiser, S., Müller, A., Lundby, C., & Maggiorini, M. (2024). Beta-adrenergic blockade increases pulmonary vascular resistance and causes exaggerated hypoxic pulmonary vasoconstriction at high altitude: a physiological study. European Heart Journal - Cardiovascular Pharmacotherapy, pvae004. https://doi.org/10.1093/ehjcvp/pvae004

Konopasek, S. M., Klinzing, S., Wendel Garcia, P. D., Hilty, M. P., & Maggiorini, M. (2023). Increased Longevity of a Novel Gas Exchanger System for Low-Flow Veno-Venous Extracorporeal CO2 Removal in Acute Hypercapnic Respiratory Failure. Blood Purification, 52(3), 275–284. https://doi.org/10.1159/000526582

Flick, M., Schreiber, T.-H., Montomoli, J., Krause, L., de Boer, H. D., Kouz, K., Scheeren, T. W. L., Ince, C., Hilty, M. P., & Saugel, B. (2022). Microcirculatory tissue perfusion during general anaesthesia and noncardiac surgery: An observational study using incident dark field imaging with automated video analysis. European Journal of Anaesthesiology, 39(7), 582–590. https://doi.org/10.1097/EJA.0000000000001699

Hilty, M. P., Favaron, E., Wendel Garcia, P. D., Ahiska, Y., Uz, Z., Akin, S., Flick, M., Arbous, S., Hofmaenner, D. A., Saugel, B., Endeman, H., Schuepbach, R. A., & Ince, C. (2022). Microcirculatory alterations in critically ill COVID-19 patients analyzed using artificial intelligence. Critical Care (London, England), 26(1), 311. https://doi.org/10.1186/s13054-022-04190-y

Hilty, M. P., Keiser, S., Wendel Garcia, P. D., Moser, A., Schuepbach, R. A., & RISC-19-ICU Investigators for Switzerland. (2022). mRNA-based SARS-CoV-2 vaccination is associated with reduced ICU admission rate and disease severity in critically ill COVID-19 patients treated in Switzerland. Intensive Care Medicine, 48(3), 362–365. https://doi.org/10.1007/s00134-021-06610-z

Jeitziner, M.-M., Moser, A., Wendel-Garcia, P. D., Exl, M. T., Keiser, S., Schuepbach, R. A., Pietsch, U., Cereghetti, S., Boroli, F., Marrel, J., Sigg, A.-A., Ksouri, H., Schott, P., Dullenkopf, A., Fleisch, I., Heise, A., Laurent, J.-C., Jakob, S. M., Hilty, M. P., … RISC-19-ICU Investigators for Switzerland. (2022). Critical care staffing ratio and outcome of COVID-19 patients requiring intensive care unit admission during the first pandemic wave: a retrospective analysis across Switzerland from the RISC-19-ICU observational cohort. Swiss Medical Weekly, 152, w30183. https://doi.org/10.4414/smw.2022.w30183

Wendel-Garcia, P. D., Moser, A., Jeitziner, M.-M., Aguirre-Bermeo, H., Arias-Sanchez, P., Apolo, J., Roche-Campo, F., Franch-Llasat, D., Kleger, G.-R., Schrag, C., Pietsch, U., Filipovic, M., David, S., Stahl, K., Bouaoud, S., Ouyahia, A., Fodor, P., Locher, P., Siegemund, M., … RISC-19-ICU Investigators. (2022). Dynamics of disease characteristics and clinical management of critically ill COVID-19 patients over the time course of the pandemic: an analysis of the prospective, international, multicentre RISC-19-ICU registry. Critical Care (London, England), 26(1), 199. https://doi.org/10.1186/s13054-022-04065-2

Düggelin, R., Maggiorini, M., Voigtsberger, S., Schwarz, U., & Hilty, M. P. (2021). Increased protocol adherence and safety during controlled normothermia as compared to hypothermia after cardiac arrest. Journal of Critical Care, 63, 146–153. https://doi.org/10.1016/j.jcrc.2020.09.019

Favaron, E., Ince, C., Hilty, M. P., Ergin, B., van der Zee, P., Uz, Z., Wendel Garcia, P. D., Hofmaenner, D. A., Acevedo, C. T., van Boven, W. J., Akin, S., Gommers, D., & Endeman, H. (2021). Capillary Leukocytes, Microaggregates, and the Response to Hypoxemia in the Microcirculation of Coronavirus Disease 2019 Patients. Critical Care Medicine, 49(4), 661–670. https://doi.org/10.1097/CCM.0000000000004862

Hilty, M. P., Moser, A., David, S., Wendel Garcia, P. D., Capaldo, G., Keiser, S., Fumeaux, T., Guerci, P., Montomoli, J., Van Boeckel, T. P., Jeitziner, M.-M., Que, Y.-A., Jakob, S., Schüpbach, R. A., & RISC-19-ICU Investigators For Switzerland. (2021). Near real-time observation reveals increased prevalence of young patients in the ICU during the emerging third SARS-CoV-2 wave in Switzerland. Swiss Medical Weekly, 151, w20553. https://doi.org/10.4414/smw.2021.20553

Montomoli, J., Romeo, L., Moccia, S., Bernardini, M., Migliorelli, L., Berardini, D., Donati, A., Carsetti, A., Bocci, M. G., Wendel Garcia, P. D., Fumeaux, T., Guerci, P., Schüpbach, R. A., Ince, C., Frontoni, E., Hilty, M. P., & RISC-19-ICU Investigators. (2021). Machine learning using the extreme gradient boosting (XGBoost) algorithm predicts 5-day delta of SOFA score at ICU admission in COVID-19 patients. Journal of Intensive Medicine, 1(2), 110–116. https://doi.org/10.1016/j.jointm.2021.09.002

Hilty, M. P., Akin, S., Boerma, C., Donati, A., Erdem, Ö., Giaccaglia, P., Guerci, P., Milstein, D. M., Montomoli, J., Toraman, F., Uz, Z., Veenstra, G., & Ince, C. (2020). Automated Algorithm Analysis of Sublingual Microcirculation in an International Multicentral Database Identifies Alterations Associated With Disease and Mechanism of Resuscitation. Critical Care Medicine, 48(10), e864–e875. https://doi.org/10.1097/CCM.0000000000004491

Wendel Garcia, P. D., Fumeaux, T., Guerci, P., Heuberger, D. M., Montomoli, J., Roche-Campo, F., Schuepbach, R. A., Hilty, M. P., & RISC-19-ICU Investigators. (2020). Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort. EClinicalMedicine, 25, 100449. https://doi.org/10.1016/j.eclinm.2020.100449

Hilty, M. P., Guerci, P., Ince, Y., Toraman, F., & Ince, C. (2019). MicroTools enables automated quantification of capillary density and red blood cell velocity in handheld vital microscopy. Communications Biology, 2(1), 217. https://doi.org/10.1038/s42003-019-0473-8

Hilty, M. P., Merz, T. M., Hefti, U., Ince, C., Maggiorini, M., & Pichler Hefti, J. (2019). Recruitment of non-perfused sublingual capillaries increases microcirculatory oxygen extraction capacity throughout ascent to 7126 m. The Journal of Physiology, 597(10), 2623–2638. https://doi.org/10.1113/JP277590

Hilty, M. P., Franzen, D. P., Wyss, C., Biaggi, P., & Maggiorini, M. (2017). Validation of transpulmonary thermodilution variables in hemodynamically stable patients with heart diseases. Annals of Intensive Care, 7(1), 86. https://doi.org/10.1186/s13613-017-0307-0

Hilty, M. P., Pichler, J., Ergin, B., Hefti, U., Merz, T. M., Ince, C., & Maggiorini, M. (2017). Assessment of endothelial cell function and physiological microcirculatory reserve by video microscopy using a topical acetylcholine and nitroglycerin challenge. Intensive Care Medicine Experimental, 5(1), 26. https://doi.org/10.1186/s40635-017-0139-0

Hilty, M. P., Riva, T., Cottini, S. R., Kleinert, E.-M., Maggiorini, A., & Maggiorini, M. (2017). Low flow veno-venous extracorporeal CO2 removal for acute hypercapnic respiratory failure. Minerva Anestesiologica, 83(8), 812–823. https://doi.org/10.23736/S0375-9393.17.11524-5

Hilty, M. P., Müller, A., Flück, D., Siebenmann, C., Rasmussen, P., Keiser, S., Auinger, K., Lundby, C., & Maggiorini, M. (2016). Effect of Increased Blood Flow on Pulmonary Circulation Before and During High Altitude Acclimatization. High Altitude Medicine & Biology, 17(4), 305–314. https://doi.org/10.1089/ham.2016.0004

Hilty, M. P., Zügel, S., Schoeb, M., Auinger, K., Dehnert, C., & Maggiorini, M. (2016). Soluble Urokinase-Type Plasminogen Activator Receptor Plasma Concentration May Predict Susceptibility to High Altitude Pulmonary Edema. Mediators of Inflammation, 2016, 1942460. https://doi.org/10.1155/2016/1942460

Hilty, M. P., Behrendt, I., Benneker, L. M., Martinolli, L., Stoupis, C., Buggy, D. J., Zimmermann, H., & Exadaktylos, A. K. (2008). Pelvic radiography in ATLS algorithms: A diminishing role? World Journal of Emergency Surgery: WJES, 3, 11. https://doi.org/10.1186/1749-7922-3-11

Brouwer, F., Ince, C., Pols, J., Uz, Z., Hilty, M. P., & Arbous, M. S. (2024). The microcirculation in the first days of ICU admission in critically ill COVID-19 patients is influenced by severity of disease. Scientific Reports, 14(1), 6454. https://doi.org/10.1038/s41598-024-56245-5

Eastwood, G., Nichol, A. D., Hodgson, C., Parke, R. L., McGuinness, S., Nielsen, N., Bernard, S., Skrifvars, M. B., Stub, D., Taccone, F. S., Archer, J., Kutsogiannis, D., Dankiewicz, J., Lilja, G., Cronberg, T., Kirkegaard, H., Capellier, G., Landoni, G., Horn, J., … TAME Study Investigators. (2023). Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest. The New England Journal of Medicine, 389(1), 45–57. https://doi.org/10.1056/NEJMoa2214552

Erdem, Ö., de Graaff, J. C., Hilty, M. P., Kraemer, U. S., de Liefde, I. I., van Rosmalen, J., Ince, C., Tibboel, D., & Kuiper, J. W. (2023). Microcirculatory Monitoring in Children with Congenital Heart Disease Before and After Cardiac Surgery. Journal of Cardiovascular Translational Research. https://doi.org/10.1007/s12265-023-10407-4

Latul, Y. P., Vodegel, E. V., Kastelein, A. W., Alkemade, L., Ras, L., Hilty, M. P., Favaron, E., Ince, Y., Ince, C., Jeffery, S., Guler, Z., & Roovers, J.-P. W. R. (2023). The effect of CO2 laser therapy on vaginal microcirculatory parameters in an animal model for genitourinary syndrome of menopause. Neurourology and Urodynamics, 42(6), 1381–1389. https://doi.org/10.1002/nau.25227

Reinhold, I., Teasca, L., Rodriguez, E. R., Berney, T., Mueller, N. J., Hilty, M. P., Andermatt, R., Saro, F., Dutkowski, P., Müllhaupt, B., van Delden, C., & Study (STCS), S. T. C. (2023). Donor-derived fulminant herpes simplex virus hepatitis after liver transplantation: Two cases and review of literature. Transplant Infectious Disease, e14080, e14080. https://doi.org/10.1111/tid.14080

Seiler, T., Nakas, C. T., Brill, A.-K., Hefti, U., Hilty, M. P., Perret-Hoigné, E., Sailer, J., Kabitz, H.-J., Merz, T. M., & Pichler Hefti, J. (2023). Do cardiopulmonary exercise tests predict summit success and acute mountain sickness? A prospective observational field study at extreme altitude. British Journal of Sports Medicine, bjsports-2022-106211. https://doi.org/10.1136/bjsports-2022-106211

Uz, Z., Dilken, O., Milstein, D. M. J., Hilty, M. P., de Haan, D., Ince, Y., Shen, L., Houtzager, J., Franken, L. C., van Gulik, T. M., & Ince, C. (2023). Identifying a sublingual triangle as the ideal site for assessment of sublingual microcirculation. Journal of Clinical Monitoring and Computing, 37(2), 639–649. https://doi.org/10.1007/s10877-022-00936-9

von Groote, T., Meersch, M., Romagnoli, S., Ostermann, M., Ripollés-Melchor, J., Schneider, A. G., Vandenberghe, W., Monard, C., De Rosa, S., Cattin, L., Rahmel, T., Adamzik, M., Parise, D., Candela-Toha, A., Haaker, J. G., Göbel, U., Bernard, A., Lumlertgul, N., Fernández-Valdes-Bango, P., … BigpAK-2 Investigators. (2023). Biomarker-guided intervention to prevent acute kidney injury after major surgery (BigpAK-2 trial): study protocol for an international, prospective, randomised controlled multicentre trial. BMJ Open, 13(3), e070240. https://doi.org/10.1136/bmjopen-2022-070240

Wendel-Garcia, P. D., Eberle, B., Kleinert, E.-M., Hilty, M. P., Blumenthal, S., Spanaus, K., Fodor, P., & Maggiorini, M. (2023). Effects of enhanced adsorption haemofiltration versus haemoadsorption in severe, refractory septic shock with high levels of endotoxemia: the ENDoX bicentric, randomized, controlled trial. Annals of Intensive Care, 13(1), 127. https://doi.org/10.1186/s13613-023-01224-8

Güven, G., Uz, Z., Hilty, M. P., Bilecenoğlu, B., Akin, Șakir, Ince, Y., & Ince, C. (2022). Morphologic Mapping of the Sublingual Microcirculation in Healthy Volunteers. Journal of Vascular Research, 1–10. https://doi.org/10.1159/000522394

Mairpady Shambat, S., Gómez-Mejia, A., Schweizer, T. A., Huemer, M., Chang, C.-C., Acevedo, C., Bergada-Pijuan, J., Vulin, C., Hofmaenner, D. A., Scheier, T. C., Hertegonne, S., Parietti, E., Miroshnikova, N., Wendel Garcia, P. D., Hilty, M. P., Buehler, P. K., Schuepbach, R. A., Brugger, S. D., & Zinkernagel, A. S. (2022). Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19. PLoS Pathogens, 18(1), e1010176. https://doi.org/10.1371/journal.ppat.1010176

Soomann, M., Wendel-Garcia, P. D., Kaufmann, M., Grazioli, S., Perez, M.-H., Hilty, M. P., André, M. C., & Brotschi, B. (2022). The SARS-CoV-2 Pandemic Impacts the Management of Swiss Pediatric Intensive Care Units. Frontiers in Pediatrics, 10, 761815. https://doi.org/10.3389/fped.2022.761815

Buehler, P. K., Zinkernagel, A. S., Hofmaenner, D. A., Wendel Garcia, P. D., Acevedo, C. T., Gómez-Mejia, A., Mairpady Shambat, S., Andreoni, F., Maibach, M. A., Bartussek, J., Hilty, M. P., Frey, P. M., Schuepbach, R. A., & Brugger, S. D. (2021). Bacterial pulmonary superinfections are associated with longer duration of ventilation in critically ill COVID-19 patients. Cell Reports. Medicine, 2(4), 100229. https://doi.org/10.1016/j.xcrm.2021.100229

Henzi, A., Kleger, G.-R., Hilty, M. P., Wendel Garcia, P. D., Ziegel, J. F., & RISC-19-ICU Investigators for Switzerland. (2021). Probabilistic analysis of COVID-19 patients’ individual length of stay in Swiss intensive care units. PloS One, 16(2), e0247265. https://doi.org/10.1371/journal.pone.0247265

Hofmaenner, D. A., Wendel Garcia, P. D., Duvnjak, B., Chakrakodi, B., Maier, J. D., Huber, M., Huder, J., Wolfensberger, A., Schreiber, P. W., Schuepbach, R. A., Zinkernagel, A. S., Buehler, P. K., Brugger, S. D., & COVID-19 ICU-Research Group Zurich. (2021). Bacterial but no SARS-CoV-2 contamination after terminal disinfection of tertiary care intensive care units treating COVID-19 patients. Antimicrobial Resistance and Infection Control, 10(1), 11. https://doi.org/10.1186/s13756-021-00885-z

Maibach, M. A., Allam, A., Hilty, M. P., Perez Gonzalez, N. A., Buehler, P. K., Wendel Garcia, P. D., Brugger, S. D., Ganter, C. C., CoViD-19 ICU-Research Group Zurich, RISC-19-ICU Investigators, Krauthammer, M., Schuepbach, R. A., & Bartussek, J. (2021). How to Synchronize Longitudinal Patient Data With the Underlying Disease Progression: A Pilot Study Using the Biomarker CRP for Timing COVID-19. Frontiers in Medicine, 8, 607594. https://doi.org/10.3389/fmed.2021.607594

Tavy, A. L., de Bruin, A. F., Boerma, E. C., Ince, C., Hilty, M. P., Noordzij, P. G., Boerma, D., & van Iterson, M. (2021). Association between serosal intestinal microcirculation and blood pressure during major abdominal surgery. Journal of Intensive Medicine. https://doi.org/10.1016/j.jointm.2021.03.003

Tobler, M., Nakas, C. T., Hilty, M. P., Huber, A., Merz, T. M., & Pichler Hefti, J. (2021). Plasmatic hemostasis at very high altitude – a thrombelastometric approach. Health Prmot Phys Act, 17(4), 6–17. https://doi.org/10.5604/01.3001.0015.5749

Wendel Garcia, P. D., Aguirre-Bermeo, H., Buehler, P. K., Alfaro-Farias, M., Yuen, B., David, S., Tschoellitsch, T., Wengenmayer, T., Korsos, A., Fogagnolo, A., Kleger, G.-R., Wu, M. A., Colombo, R., Turrini, F., Potalivo, A., Rezoagli, E., Rodríguez-García, R., Castro, P., Lander-Azcona, A., … RISC-19-ICU Investigators. (2021). Implications of early respiratory support strategies on disease progression in critical COVID-19: a matched subanalysis of the prospective RISC-19-ICU cohort. Critical Care, 25(1), 175. https://doi.org/10.1186/s13054-021-03580-y

Wendel Garcia, P. D., Hilty, M. P., Held, U., Kleinert, E.-M., & Maggiorini, M. (2021). Cytokine adsorption in severe, refractory septic shock. Intensive Care Medicine, 47(11), 1334–1336. https://doi.org/10.1007/s00134-021-06512-0

Combes, A., Auzinger, G., Capellier, G., du Cheyron, D., Clement, I., Consales, G., Dabrowski, W., De Bels, D., de Molina Ortiz, F. J. G., Gottschalk, A., Hilty, M. P., Pestaña, D., Sousa, E., Tully, R., Goldstein, J., & Harenski, K. (2020). ECCO2R therapy in the ICU: consensus of a European round table meeting. Critical Care (London, England), 24(1), 490. https://doi.org/10.1186/s13054-020-03210-z

Ergin, B., Guerci, P., Uz, Z., Westphal, M., Ince, Y., Hilty, M. P., & Ince, C. (2020). Hemodilution causes glycocalyx shedding without affecting vascular endothelial barrier permeability in rats. Journal of Clinical and Translational Research, 5(5), 243–252. https://doi.org/10.18053/jctres.05.202005.004

Guerci, P., Ergin, B., Kandil, A., Ince, Y., Heeman, P., Hilty, M. P., Bakker, J., & Ince, C. (2020). Resuscitation with PEGylated carboxyhemoglobin preserves renal cortical oxygenation and improves skeletal muscle microcirculatory flow during endotoxemia. American Journal of Physiology. Renal Physiology, 318(5), F1271–F1283. https://doi.org/10.1152/ajprenal.00513.2019

Haider, T., Diaz, V., Albert, J., Alvarez-Sanchez, M., Thiersch, M., Maggiorini, M., Hilty, M. P., Spengler, C. M., & Gassmann, M. (2020). A Single 60.000 IU Dose of Erythropoietin Does Not Improve Short-Term Aerobic Exercise Performance in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial. Frontiers in Physiology, 11, 537389. https://doi.org/10.3389/fphys.2020.537389

Klinzing, S., Hilty, M. P., Bechtel-Grosch, U., Schuepbach, R. A., Bühler, P., & Brandi, G. (2020). Dynamic optic nerve sheath diameter changes upon moderate hyperventilation in patients with traumatic brain injury. Journal of Critical Care, 56, 229–235. https://doi.org/10.1016/j.jcrc.2020.01.008

Zhao, C., Tepekule, B., Criscuolo, N. G., Wendel Garcia, P. D., Hilty, M. P., RISC-19-ICU Consortium Investigators In Switzerland, Fumeaux, T., & Van Boeckel, T. (2020). icumonitoring.ch: a platform for short-term forecasting of intensive care unit occupancy during the COVID-19 epidemic in Switzerland. Swiss Medical Weekly, 150, w20277. https://doi.org/10.4414/smw.2020.20277

Guerci, P., Ergin, B., Kapucu, A., Hilty, M. P., Jubin, R., Bakker, J., & Ince, C. (2019). Effect of Polyethylene-glycolated Carboxyhemoglobin on Renal Microcirculation in a Rat Model of Hemorrhagic Shock. Anesthesiology, 131(5), 1110–1124. https://doi.org/10.1097/ALN.0000000000002932

Fisher, J. P., Flück, D., Hilty, M. P., & Lundby, C. (2018). Carotid chemoreceptor control of muscle sympathetic nerve activity in hypobaric hypoxia. Experimental Physiology, 103(1), 77–89. https://doi.org/10.1113/EP086493

Roach, R. C., Hackett, P. H., Oelz, O., Bärtsch, P., Luks, A. M., MacInnis, M. J., Baillie, J. K., & Lake Louise AMS Score Consensus Committee. (2018). The 2018 Lake Louise Acute Mountain Sickness Score. High Altitude Medicine & Biology, 19(1), 4–6. https://doi.org/10.1089/ham.2017.0164

Uz, Z., Ince, C., Guerci, P., Ince, Y., P Araujo, R., Ergin, B., Hilty, M. P., van Gulik, T. M., & de Mol, B. A. (2018). Recruitment of sublingual microcirculation using handheld incident dark field imaging as a routine measurement tool during the postoperative de-escalation phase-a pilot study in post ICU cardiac surgery patients. Perioperative Medicine (London, England), 7, 18. https://doi.org/10.1186/s13741-018-0091-x

von Wolff, M., Nakas, C. T., Tobler, M., Merz, T. M., Hilty, M. P., Veldhuis, J. D., Huber, A. R., & Pichler Hefti, J. (2018). Adrenal, thyroid and gonadal axes are affected at high altitude. Endocrine Connections, 7(10), 1081–1089. https://doi.org/10.1530/EC-18-0242

Keiser, S., Meinild-Lundby, A.-K., Steiner, T., Trösch, S., Rauber, S., Krafft, A., Burkhardt, T., Hilty, M. P., Siebenmann, C., Wehrlin, J. P., & Lundby, C. (2017). Detection of blood volumes and haemoglobin mass by means of CO re-breathing and indocyanine green and sodium fluorescein injections. Scandinavian Journal of Clinical and Laboratory Investigation, 77(3), 164–174. https://doi.org/10.1080/00365513.2016.1271908

Rasmussen, P., Widmer, M., Hilty, M. P., Hug, M., Sørensen, H., Ogoh, S., Sato, K., Secher, N. H., Maggiorini, M., & Lundby, C. (2017). Thermodilution-determined Internal Jugular Venous Flow. Medicine and Science in Sports and Exercise, 49(4), 661–668. https://doi.org/10.1249/MSS.0000000000001143

Siebenmann, C., Rasmussen, P., Hug, M., Keiser, S., Flück, D., Fisher, J. P., Hilty, M. P., Maggiorini, M., & Lundby, C. (2017). Parasympathetic withdrawal increases heart rate after 2 weeks at 3454 m altitude. The Journal of Physiology, 595(5), 1619–1626. https://doi.org/10.1113/JP273726

Dandanell, S., Oberholzer, L., Keiser, S., Andersen, A. B., Haider, T., Hilty, M. P., Meinild-Lundby, A. K., & Lundby, C. (2016). Effect of alterations in blood volume with bed rest on glucose tolerance. Journal of Applied Physiology (Bethesda, Md.: 1985), 121(5), 1098–1105. https://doi.org/10.1152/japplphysiol.00624.2016

Jacobs, R. A., Lundby, A.-K. M., Fenk, S., Gehrig, S., Siebenmann, C., Flück, D., Kirk, N., Hilty, M. P., & Lundby, C. (2016). Twenty-eight days of exposure to 3454 m increases mitochondrial volume density in human skeletal muscle. The Journal of Physiology, 594(5), 1151–1166. https://doi.org/10.1113/JP271118

Keiser, S., Flück, D., Hüppin, F., Stravs, A., Hilty, M. P., & Lundby, C. (2015). Heat training increases exercise capacity in hot but not in temperate conditions: a mechanistic counter-balanced cross-over study. American Journal of Physiology. Heart and Circulatory Physiology, 309(5), H750-761. https://doi.org/10.1152/ajpheart.00138.2015

Siebenmann, C., Cathomen, A., Hug, M., Keiser, S., Lundby, A. K., Hilty, M. P., Goetze, J. P., Rasmussen, P., & Lundby, C. (2015). Hemoglobin mass and intravascular volume kinetics during and after exposure to 3,454-m altitude. Journal of Applied Physiology (Bethesda, Md.: 1985), 119(10), 1194–1201. https://doi.org/10.1152/japplphysiol.01121.2014

Flück, D., Braz, I. D., Keiser, S., Hüppin, F., Haider, T., Hilty, M. P., Fisher, J. P., & Lundby, C. (2014). Age, aerobic fitness, and cerebral perfusion during exercise: role of carbon dioxide. American Journal of Physiology. Heart and Circulatory Physiology, 307(4), H515-523. https://doi.org/10.1152/ajpheart.00177.2014

Flick, M., Hilty, M. P., Duranteau, J., & Saugel, B. (2024). The microcirculation in perioperative medicine: a narrative review. British Journal of Anaesthesia, 132(1), 25–34. https://doi.org/10.1016/j.bja.2023.10.033

Montomoli, J., Hilty, M. P., & Ince, C. (2022). Artificial intelligence in intensive care: moving towards clinical decision support systems. Minerva Anestesiologica, 88(12), 1066–1072. https://doi.org/10.23736/S0375-9393.22.16739-8

Capaldo, G., Ince, C., & Hilty, M. P. (2021). The clinical relevance of high-altitude microcirculation studies: the example of COVID-19. Annual Update in Intensive Care and Emergency Medicine, 2021(2021), 103–110. https://doi.org/10.1007/978-3-030-73231-8_10

Vincent, J.-L. (Ed.). (2021). Annual Update in Intensive Care and Emergency Medicine 2021. Springer International Publishing. https://doi.org/10.1007/978-3-030-73231-8

Guven, G., Hilty, M. P., & Ince, C. (2020). Microcirculation: Physiology, Pathophysiology, and Clinical Application. Blood Purification, 49(1–2), 143–150. https://doi.org/10.1159/000503775

Hilty, M. P., & Ince, C. (2020). Automated quantification of tissue red blood cell perfusion as a new resuscitation target. Current Opinion in Critical Care, 26(3), 273–280. https://doi.org/10.1097/MCC.0000000000000725

Hilty, M. P., & Ince, C. (2020). Microtools to Identify and Resuscitate Microcirculatory Dysfunction in Critically Ill Patients. ICU Management and Practice, 20(3). https://healthmanagement.org/c/icu/issuearticle/microtools-to-identify-and-resuscitate-microcirculatory-dysfunction-in-critically-ill-patients

Favaron, E., Montomoli, J., Hilty, M. P., & Ince, C. (2019). Fluid management in the perioperative setting: mind the kidney. Journal of Emergency and Critical Care Medicine, 3(50). https://doi.org/10.21037/jeccm.2019.08.09

Maggiorini, M., & Hilty, M. P. (2017). [High altitude pulmonary edema - A clinical overview]. Wiener Medizinische Wochenschrift - Skriptum, 14(8), 8–12. http://www.springer.com/cda/content/document/cda_downloaddocument/Skriptum_8_2017_%C3%96GP.pdf?SGWID=0-0-45-1619669-p173827603

Hilty, M. P., & Maggiorini, M. (2012). Höhenkrankheit - Empfehlungen zu Prävention und Therapie. Cardiovasc, Springer Medizin, 11(3), 6–10.

Lupi, E., Arrigo, M., Hilty, M. P., Eppinger, N., Ruschitzka, F., Rickli, H., & Flammer, A. J. (2018). Fulminante Myokarditis bei Influenza. Swiss Medical Forum, 18(16), 355–358. https://doi.org/10.4414/smf.2018.03216

Stark, D., Stiller, R., Xie, M., Weber, D., Maggiorini, M., & Hilty, M. P. (2018). Preserving fertility in an unconscious patient with Goodpasture syndrome-medicolegal and ethical aspects. Journal of Intensive Care, 6, 40. https://doi.org/10.1186/s40560-018-0311-y

Hilty, M. P., Halama, M., Zimmermann, A.-K., Maggiorini, M., & Geier, A. (2015). Ulcerating Ileocolitis in Severe Amatoxin Poisoning. Case Reports in Gastrointestinal Medicine, 2015, 632085. https://doi.org/10.1155/2015/632085

Hilty, M. P., Widmer, M. K., Carrel, T., & Schmidli, J. (2005). Aneurysma der Vena poplitea. Swiss Medical Forum, 5(16), 419–420. https://doi.org/10.4414/smf.2005.05526

Hilty, M. P., & Jung, C. (2023). Tissue oxygenation: how to measure, how much to target. Intensive Care Medicine Experimental, 11(1), 64. https://doi.org/10.1186/s40635-023-00551-1

Hilty, M. P., & David, S. (2021). Mind the Gap - From Big Data to Physiology (and Back). Respiratory Care, 66(4), 701–702. https://doi.org/10.4187/respcare.09008

Hilty, M. P., Duranteau, J., Montomoli, J., Yeh, T. Y.-C., & Ince, C. (2023). A microcirculation-guided trial doomed to fail. Intensive Care Medicine. https://doi.org/10.1007/s00134-023-07223-4

Hilty, M. P., Hefti, U., Brugger, H., & Bouzat, P. (2020). Letter to the Editor: Preacclimatization for Expeditions to Extreme Altitude: An Opinion Position from the Union Internationale des Associations d’Alpinisme Medical Commission. High Altitude Medicine & Biology, 21(3), 303–304. https://doi.org/10.1089/ham.2020.0029

Strapazzon, G., Hilty, M. P., Bouzat, P., Pratali, L., Brugger, H., & Rauch, S. (2020). To compare the incomparable: COVID-19 pneumonia and high-altitude disease. The European Respiratory Journal, 55(6), 2001362. https://doi.org/10.1183/13993003.01362-2020

Hilty, M. P., Riva, T., Cottini, S. R., Kleinert, E.-M., Maggiorini, A., & Maggiorini, M. (2018). Patient selection for extracorporeal CO2 removal: a task as challenging as for ECMO therapy. Minerva Anestesiologica, 84(3), 410–411. https://doi.org/10.23736/S0375-9393.18.12705-2

Hilty, M. P., Zügel, S., Schoeb, M., Auinger, K., Dehnert, C., & Maggiorini, M. (2018). Response to: Comment on “Soluble Urokinase-Type Plasminogen Activator Receptor Plasma Concentration May Predict Susceptibility to High Altitude Pulmonary Edema.” Mediators of Inflammation, 2018, 8036759. https://doi.org/10.1155/2018/8036759

Bertacchi, M., Wendel Garcia, P., Ince, C., Maggioni, M., & Hilty, M. (2020). Sublingual Capillary De-recruitment in Resuscitated Patients with Circulatory Shock. Swiss Medical Forum, 40(Supplementum 68), 4S.

Kiyatkin, M., Ji, R., Favaron, E., Hilty, M. P., Colombo, P., Moitra, V., & Bakker, J. (2020). Characterizetion of sublingual microcirculation after left ventricular assist device implantation. Critical Care Medicine, 48, 104. https://doi.org/10.1097/01.ccm.0000619332.02975.cb

Wendel Garcia, P., Hilty, M., Held, U., Kleinert, E., & Maggioni, M. (2020). Cytokine Adsorption in Severe Therapy-Refractory Septic Shock: An Ambispective Matched Cohort Study. Swiss Medical Forum, 40(Supplementum 68), 5S.

Hilty, M. P., Giaccaglia, P., Akin, S., Erdem, O., Ergin, B., Milstein, D. M. J., Toraman, F., Uz, Z., Veenstra, G., & Ince, C. (2019). Validation of automated software for analysis of the sublingual microcirculation in clinical and experimental settings: 39th International Symposium on Intensive Care and Emergency Medicine. Critical Care (London, England), 23(Suppl 2), 72. https://doi.org/10.1186/s13054-019-2358-0

Wendel Garcia, P., Bardelli, P., Kleinert, E., Bader, P., Freiburghaus, R., Schmid, U., Heim, S., Hilty, M., Spanaus, K., von Eckardstein, A., & Maggioni, M. (2019). Prediction of mortality and multi-organ dysfunction in the ICU through MR-proADM: A prospective single-center experience. Swiss Medical Forum, 39(Supplementum 67), 73S.

Wendel Garcia, P., Brüllmann, G., Keller, M., Auinger, K., Hilty, M., & Maggioni, M. (2019). Assessing the precision of a semiinvasive, extended hemodynamic monitoring device for cardiac output estimation in critically ill: A prospective single-center study. Swiss Medical Forum, 39(Supplementum 67), 26S.

Wendel Garcia, P., Freiburghaus, R., Hilty, M., & Maggioni, M. (2019). Prediction of hypotensive events in a medical ICU population by use of the Hypotension Probability Index. Swiss Medical Forum, 39(Supplementum 67), 74S.

Wendel Garcia, P., Hilty, M., Ganter, C., & Maggioni, M. (2019). Voriconazole and liposomal Amphotericin B adsorption by the Cytosorb-Adsorber: Pharmacokinetic modelling of a case. Swiss Medical Forum, 39(Supplementum 67), 53S.

Wenger, U., Hilty, M., Wendel Garcia, P., Nater, H., Stark, D., & Maggioni, M. (2019). Standardizing lung protective mechanical ventilation on ECMO: Automatic, closed loop ventilation in patients with ARDS or cardiogenic shock. Swiss Medical Forum, 39(Supplementum 67), 70S.

Arend, S., Ince, C., Van Assen, M., Fevzi, T., & Hilty, M. P. (2018). A software tool to quantify capillary hematocrit and microvascular hemodilution in sublingual incident dark field microscopy video clips: 38th International Symposium on Intensive Care and Emergency Medicine. Critical Care, 22(1), 82,P278. https://doi.org/10.1186/s13054-018-1973-5

Hilty, M. P., Arend, S., Van Assen, M., Toraman, F., & Ince, C. (2018). A software tool to quantify capillary blood volume and absolute red blood cell velocity in sublingual incident dark field microscopy video clips. Intensive Care Medicine Experimental, 6(Supplement 2:0333), 172–173. https://doi.org/10.1186/s40635-018-0201-6

Hilty, M. P., Konopasek, S. M., & Maggiorini, M. (2018). Prediction of mortality in patients treated with low flow veno-venous extracorporeal CO2 removal for acute hypercapnic respiratory failure. Swiss Medical Forum, 38(Supplementum 66), 24S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-66.pdf

Hilty, M. P., Wendel Garcia, P. D., Kleinert, E.-M., & Maggiorini, M. (2018). Combined low flow veno-venous extracorporeal CO2 removal and continuous renal replacement therapy: a case series. Swiss Medical Forum, 38(Supplementum 66), 31S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-66.pdf

Konopasek, S. M., Hilty, M. P., & Maggiorini, M. (2018). Viability and efficiency of a high longevity gas exchanger system for low flow veno- venous extracorporeal CO2 removal in acute hypercapnic respiratory failure. Swiss Medical Forum, 38(Supplementum 66), 17S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-66.pdf

Düggelin, R., Voigtsberger, S., Maggiorini, M., & Hilty, M. P. (2017). Comparison of two different target temperature management protocols (32-34°C versus 36°C) following resuscitation after cardiac arrest. Swiss Medical Forum, 37(Supplementum 65), 17S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-65.pdf

Nater, H., Hilty, M. P., Stark, D., Hauffe, T., Christe, N., Furrer, F., Wenger, U., & Maggiorini, M. (2017). Dreieckinteraktion „Patient –  INTELLiVENT-ASV – ECMO/ECLS“ bei beatmeten Patienten mit ARDS oder kardiogenem Schock. Swiss Medical Forum, 37(Supplementum 65), 35S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-65.pdf

Roach, R. C., Wagner, P. D., Ainslie, P. N., & Hackett, P. H. (2017). Translation in Progress: Hypoxia 2017. Journal of Applied Physiology (Bethesda, Md.: 1985), 123(4), 922–925. https://doi.org/10.1152/japplphysiol.00846.2017

Stark, D., Stiller, R., Xie, M., Weber, D., Theler, J., Maggiorini, M., & Hilty, M. P. (2017). Preserving fertility in an unconscious patient with Goodpasture Syndrome – medicolegal and ethical aspects. Swiss Medical Forum, 73(Supplementum 65), 39S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-65.pdf

Hauffe, T., Hilty, M. P., Kleinert, E.-M., & Maggiorini, M. (2016). High  Prevalence of  Severe Vitamin D Deficiency in Medical ICU patients - a marker for ICU  mortality? Swiss Medical Forum, 38(Supplementum 64), 47S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-64.pdf

Hilty, M., Martinolli, L., Behrendt, I., Stoupis, C., Zimmermann, H., & Exadaktylos, A. (2016). Is the standard emergency room pelvic x-ray according to ATLS still up-to-date? British Journal of Surgery, 93(9), 1163. https://insights.ovid.com/british-surgery/bjsu/2006/09/000/standard-emergency-room-pelvic-ray-according-atls/60/00002413.

Huser, M. C., Hilty, M. P., Balabanov, S., Trachsel, C., Bächli, E., & Maggiorini, M. (2015). Hemophagocytic lymphohistiocytosis  as a cause for  severe systemic  inflammatory response  syndrome. Swiss Medical Forum, 36(Supplementum 63), 142. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-63.pdf

Wong, A., Donadello, K., Thiessen, S., Aissaoui, N., Bollen Pinto, B., De Pascale, G., Hilty, M., Lane, K., Mendoza, M., Schellongowski, P., Shepherd, S., Weidanz, F., Weiss, B., Werner, J., & Prisco, L. (2015). Intensive care medicine in europe: the state of the training art. Intensive Care Medicine Experimental, 3(Suppl 1), A859. https://doi.org/10.1186/2197-425X-3-S1-A859

Hilty, M. P., Franzen, D. P., Wyss, C., Biaggi, P., & Maggiorini, M. (2014). Global end diastolic volume does not reflect end diastolic volume in patients with cardiac disease. Swiss Medical Forum, 24(Supplementum 62), 61. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-62.pdf

Hilty, M. P., Riva, T., Cottini, S. R., Kleinert, E.-M., Maggiorini, A., & Maggiorini, M. (2013). Ultra-Low flow veno-venous extracorporeal CO2 removal in acute hypercapnic respiratory failure. Swiss Medical Forum, 13(Supplementum 61), 3S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-61.pdf

Auinger, K., Hilty, M. P., Caduff, C., Auf der Maur, F., Kleinert, E.-M., & Maggiorini, M. (2012). Uncalibrated pulse contour cardiac output measurement devices overestimate effective cardiac output. Swiss Medical Forum, 12(Supplementum 59), 15S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-59.pdf

Hilty, M. P., Eberle, B., & Maggiorini, M. (2012). Endotoxin activity in sepsis and septic shock. Intensive Care Medicine, 38(Supplement 1), S98. https://doi.org/10.1007/s00134-012-2683-0

Hilty, M. P., Eberle, B., & Maggiorini, M. (2012). Endotoxin activity in sepsis and septic shock. Swiss Medical Forum, 12(Supplementum 59), 15S-16S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-59.pdf

Hilty, M. P., Franzen, D. P., Wyss, C., Biaggi, P., Schmied, C., & Maggiorini, M. (2012). Transpulmonary thermodilution in severe mitral regurgitation. Swiss Medical Forum, 12(Supplementum 59), 15S. https://medicalforum.ch/fileadmin/content/Supplements/Swiss-Medical-Forum-Supplementum-59.pdf

Evangelopoulos, D., Hilty, M., Benneker, L., Zimmermann, H., & Exadaktylos, A. (2011). ATLS and Pelvic Radiography Guidelines. How Good Is Clinical Examination Compared to Conventional Radiography? Orthopaedic Proceedings, 93-B(SUPP III), 370–370. http://www.bjjprocs.boneandjoint.org.uk/content/93-B/SUPP_III/370.4

Mueller, A., Hilty, M., Benneker, L., Martinolli, L., Eggli, S., Zimmermann, H., & Exadaktylos, A. (2007). Full body digital X-ray in trauma and resuscitation-an experience report of the modified Bernese ATLS (R) algorithm. BRITISH JOURNAL OF SURGERY, 94, 770–770. http://scholar.google.com/scholar?cluster=5144445726965199246&hl=en&oi=scholarr.

Hilty, M., Martinolli, L., Behrendt, I., Stoupis, C., Zimmermann, H., & Exadaktylos, A. (2006). Do we still need pelvic X-rays in all polytraumatized patients? European Journal of Emergency Medicine, 13(5), A2–A3. http://journals.lww.com/euro-emergencymed/Fulltext/2006/10000/Do_we_still_need_pelvic_X_rays_in_all.25.aspx