Zotero works with Firefox 2.0 or 3.0, Netscape Navigator 9.0, and Flock 0.9.1 for Windows, Mac, or Linux.

No. We cannot reproduce the functionality of Zotero in most other browsers due to their lack of equivalent support for extensions. Many of Zotero's advanced features, such as the ability to sense and grab citations from web pages, are only possible because Firefox exposes all of its underlying functionality to extension developers. Microsoft and many other browser creators don’t allow extension developers to call on more than a tiny fraction of their code. This explanation may be no solace for inveterate IE users, but we hope that IE users who like the functionality of Zotero will give Firefox a try.