Steve Holt : Curriculum Vitae

Papers

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Extramedullary haematopoeisis in the renal parenchyma as a cause of acute renal failure in myelofibrosis.

Holt, S.G., Field, P., Carmichael, P., Mehta, A., Jarmulowicz, M., Clarke, D., Hilson, A. and  Burns, A.

Nephrology, Dialysis, Transplantation (1995)10:1438-1440.

 

Calcific deposits at the injection site when calcium heparin is given subcutaneously to patients with high serum phosphates.

Holt, S.G., Buscombe, J. and Sweny, P.

British Medical Journal (1996) 7071 (313): 156.

 

Bile acids, oxidative stress, and renal function in biliary obstruction

Bomzon, A., Holt, S. and Moore,K.

Seminars in Nephrology (1997) 17:549-562.



A causative role for redox cycling of myoglobin and its inhibition by alkalinization in the pathogenesis and treatment of rhabdomyolysis-induced renal failure.

Moore, K.P., Holt, S.G., Patel, R.P., Svistunenko, D.A., Zackert, W.E., Goodier, D., Reeder, B.J., Clozel, M., Anand, R., Cooper, C.E., Morrow, J.D., Wilson, M.T., Darley-Usmar, V. and Roberts, L.J.2

Journal of Biological Chemistry (1998) 273:31731-31737.



Cytokine nephropathy and multi-organ dysfunction in lymphoma.

Holt, S., Varghese, Z., Jarmulowicz, M., Marley, R.,  Amlot, P., Hamilton, M., Davenport, A., Burns, A. and Sweny, P.

Nephrology, Dialysis, Transplantation (1998) 13:1853-1857.

 

N-Acetylcysteine Prevents the Development of the Hyperdynamic Circulation in the Portal Hypertensive Rat. 

Fernando, B., Marley, R., Holt, S.G., Anand, R., Harry, D., Sanderson, P., Smith, R. , Hamilton, G. and Moore, K.

Hepatology (1998)  28:689-694.



Increased lipid peroxidation in patients with rhabdomyolysis.

Holt, S. G., Reeder, B. J., Wilson, M. T., Harvey, S., Morrow, J. D., Roberts, L. J. 2nd and Moore, K. P.

Lancet  (1999)  353: 9160.

 

Improvement in renal function in hepatorenal syndrome with N-acetylcysteine.

Holt, S., Goodier, D., Marley, R., Patch, D., Burroughs, A., Fernando, B., Harry, D. and     Moore, K.

Lancet (1999) 353: 294-295.

 

The reappearing kidney: an unusual cause of acute renal failure.

Kingdon, E., Brunton, C., Holt, S., Buscombe, J., Hilson, A., Burns, A. and Sweny, P.

Nephrology Dialysis Transplantation (1999) 14: 1758-1760.

 

Acute cholestasis-induced renal failure: Effects of anti-oxidants and ligands for the TxA2 receptor.

Holt, S.G., Marley, R., Fernando, B., Harry, D., Anand, R., Goodier, D. and Moore, K.P.

Kidney International (1999) 55: 271-277.



Chemiluminescense Based Assay for S-Nitrosoalbumin and Other Plasma S-Nitrosothiols.

Marley, R., Feelisch, M., Holt, S., Darley-Usmar, V. and Moore, K.

Free Radical Research (1999) 32:1-9.

 

Increased Sensitivity to Endotoxaemia in the Bile Duct-Ligated Cirrhotic Rat.

Harry, D., Anand, R., Holt, S., Davies, S., Marley, R., Fernando, B., Goodier, D. and  Moore,K.

Hepatology (1999) 30(5):1198-1205.



Lipoic acid prevents development of the hyperdynamic circulation in anesthetized rats with biliary cirrhosis.

Marley, R., Holt, S., Fernando, B., Harry, D., Anand, R., Goodier, D., Davies, S. and Moore, K.

Hepatology  (1999) 29:1358-1363.

 

Rhabdomyolysis.

Holt, S.G.

Critical Care Focus, 1. Renal Failure,
Ed. Galley, H.F.

BMJ Books (1999) London, UK

 

Alcoholic hepatitis-the case for intensive management.

O'Beirne, J., Patch,D., Holt, S., Hamilton, M. and Burroughs, A.K.

Postgraduate Medical Journal. (2000) 76(898):504-507.

 

Pathogenesis of renal failure in rhabdomyolysis: The role of myoglobin.

Holt, S. and Moore, K

Experimental Nephrology (2000) 8(2):72-6.

 

Pathogenesis and Treatment of Rhabdomyolysis.

Holt, S.G. and Moore,K.P

Intensive Care Medicine (2001) 27(5): 803-811.

 

Acute Renal Failure.

Holt,S.G. and Ashley, C.

Pharmaceutical Journal (2001) 266:625-628.



Atrial Thrombus and Central Venous Dialysis Catheters.

Kingdon, E., Holt, S., Davar, J., Pennell, D., Baillod, R.A., Burns, A.., Sweny, P. and   Davenport, A.

Journal of the American Society of Nephrology (2001) 38(3): 631-639.

 

Different effects of tacrolimus and cyclosporine on renal hemodynamics and blood pressure in healthy subjects.

Holt, S. and Moore, K.

Transplantation (2002) 73(5):673-674.

 



Endothelin is an important determinant of renal function in a rat model of acute liver and renal failure.

Anand, R., Harry, D., Holt, S., Milner, P., Dashwood, M., Goodier, D., Jarmulowicz, M. and Moore,K.

Gut  (2002) 50(1):111-117.

 

The potential usefulness of vitamin C as an anti-oxidant?

Holt, S. and Moore, K.

Intensive Care Medicine (2002) 28(8):1186.

 

Renal Involvement in an Anderson-Fabry heterozygote.

Kingdon, E,. Holt, S. and Burns, A.

Postgraduate Medical Journal (2002) 78(926):759.

 

Rhabdomyolysis and acute renal failure – causes and therapy.

Holt, S.G.

International Journal of Intensive Care (2002) 9(1): 17-25.

 

Simultaneous relapse of Graves' disease and minimal change glomerular disease.

Holt, S., Kingdon, E., Morganstein, D.and Sweny, P.

Nephrology Dialysis Transplantation (2002) 17(4):666-668.

 

Radiocontrast Media-Induced Renal Injury - Saline Is Effective in Prevention.

Holt, S.

Nephron (2003) 93:c5-c6.

 

Acute Transplant Rejection Induced By Blood Transfusion Reaction to Kidd blood group system.

Holt, S.G., Donaldson, H., Hazlehurst, G., Varghese, Z., Contreras, M., Kingdon, E.,       Sweny, P. and Burns, A.

Nephrology, Dialysis, Transplantation (2004) Sep.19(9):2403-2406.



Dialysis Independence After Treatment Of Extramedullary Haemopoeisis With Radiotherapy. 

Semple, D.,  Kingdon, E. and  Holt, S.

Nephrol Dial Transplant (2004) May 19(5):1310-1312.

 

The challenge of germ cell tumour therapy in dialysis and transplantation.

Dean,C., Bloomfield, D. and Holt, S.

Nephrology Dialysis Transplantation (2005) Dec.20(12):2867-2868. 

 

Treatment of unilateral obstruction reversing heavy and bilateral proteinuria.

Afzali, B., Kingdon, E. and Holt, S.G.

Nephrology Dialysis Transplantation (2005) Jan. 20(1):210-212. 

 

The Liver unit.

Holt, S.G.

Acute Renal Failure in Practice eds. Pusey,C., Allen, A. and Glyne, P.

Imperial College Press (2006)  ISBN 1-86094-216-4.

 

Granulomatous interstitial nephritis treated with a tumour necrosis factor-alpha inhibitor.

Tomlinson, L., Davies, K., Wright, D.A. and Holt, S.

Nephrology, Dialysis, Transplantation (2006) May 23: 

 

Radiotherapy for a pulmonary aspergilloma complicating p-ANCA positive small vessel vasculitis.

Glover,S., Holt, S.G., Newman, G.H. and Kingdon, E.J.

J. Infect. (2007) 215-217.

 

Renal dysfunction in liver disease.

Mckinnel, J. and Holt, S.

Medicine (2007) 35(9):521-523.

 

Aerococcus urinae as Pathogen in Peritoneal Dialysis Peritonitis a First Report.

Naghibi, M., Javaid, MM. and Holt, S.

Perit Dial Int. 2007 Nov-Dec;27(6):715-6.



The pathogenesis and treatment of Rhabdomyolysis.

Tomlinson, L. and Holt, S.

Renal Failure and Replacement Therapies (Competency-Based Critical Care series)

Eds. Blakeley, Sara 2008 ISBN: 978-1-84628-936-1

 

Audit of costs associated with the use of cinacalcet

Sheil K, Sood RB, Kingdon EJ, Holt SG

British Journal of Renal Medicine 2008 13(3); 8-11

 

Prevalence of ambulatory hypotension in elderly patients with CKD stages 3 and 4.

Tomlinson LA, Leslie A, Holt S, Rajkumar C.

 NDT (in press)

Predictors of Renal Outcome in HIV-associated Nephropathy

Post FA, Campbell LJ, Collins L, Jones, R, Siani R, Johnson L, Fisher M, Holt SG et al

Clinical Infectious Diseases 2008; 46:1282–9

Report of the Renal Association Working Party On Peritoneal Access

http://www.renal.org/pages/media/Trustees/PD%20Access%20WP%20Report%20_Final_%2021May%20081.pdf

Tomlinson LA, Leslie A, Holt S, Rajkumar C.

Prevalence of ambulatory hypotension in elderly patients with CKD stages 3 and 4.

Nephrology Dialysis Transplantation (in press)

Recent developments in HIV and the kidney

Frank A. Post and Stephen G. Holt

Current Opinion in Infectious Diseases 2009,22:43–48

Spectrum of chronic kidney disease in HIV-infected patients.

Campbell L, Ibrahim F, Fisher M, Holt S, Hendry B, Post F.

HIV Med. 2009 Feb 13

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