MeMotif: a database of linear motifs in alpha-helical transmembrane proteins
| Item Type |
Journal Article |
| Author |
Annalisa Marsico |
| Author |
Kerstin Scheubert |
| Author |
Anne Tuukkanen |
| Author |
Andreas Henschel |
| Author |
Christof Winter |
| Author |
Rainer Winnenburg |
| Author |
Michael Schroeder |
| URL |
http://www.ncbi.nlm.nih.gov/pubmed/19910368
|
| Volume |
38 |
| Issue |
Database issue |
| Pages |
D181-189 |
| Publication |
Nucleic Acids Research |
| ISSN |
1362-4962 |
| Date |
Jan 2010 |
| Extra |
| Journal Abbr |
Nucleic Acids Res |
| DOI |
10.1093/nar/gkp1042 |
| Accessed |
2009-12-30 14:29:28 |
| Library Catalog |
NCBI PubMed |
| Abstract |
Membrane proteins are important for many processes in the cell and used as main drug targets. The increasing number of high-resolution structures available makes for the first time a characterization of local structural and functional motifs in alpha-helical transmembrane proteins possible. MeMotif (http://projects.biotec.tu-dresden.de/memotif) is a database and wiki which collects more than 2000 known and novel computationally predicted linear motifs in alpha-helical transmembrane proteins. Motifs are fully described in terms of several structural and functional features and editable. Motifs contained in MeMotif can be used in different biological applications, from the identification of biochemically important functional residues which are candidates for mutagenesis experiments to the improvement of tools for transmembrane protein modeling. |
| Title |
MeMotif: a database of linear motifs in alpha-helical transmembrane proteins |
| Short Title |
MeMotif |
| Date Added |
2009-12-30 09:29 |
| Date Modified |
2009-12-30 09:29 |