HLungDB: an integrated database of human lung cancer research
| Item Type |
Journal Article |
| Author |
Lishan Wang |
| Author |
Yuanyuan Xiong |
| Author |
Yihua Sun |
| Author |
Zhaoyuan Fang |
| Author |
Li Li |
| Author |
Hongbin Ji |
| Author |
Tieliu Shi |
| URL |
http://www.ncbi.nlm.nih.gov/pubmed/19900972
|
| Volume |
38 |
| Issue |
Database issue |
| Pages |
D665-669 |
| Publication |
Nucleic Acids Research |
| ISSN |
1362-4962 |
| Date |
Jan 2010 |
| Extra |
| Journal Abbr |
Nucleic Acids Res |
| DOI |
10.1093/nar/gkp945 |
| Accessed |
2009-12-30 14:26:10 |
| Library Catalog |
NCBI PubMed |
| Abstract |
The human lung cancer database (HLungDB) is a database with the integration of the lung cancer-related genes, proteins and miRNAs together with the corresponding clinical information. The main purpose of this platform is to establish a network of lung cancer-related molecules and to facilitate the mechanistic study of lung carcinogenesis. The entries describing the relationships between molecules and human lung cancer in the current release were extracted manually from literatures. Currently, we have collected 2585 genes and 212 miRNA with the experimental evidences involved in the different stages of lung carcinogenesis through text mining. Furthermore, we have incorporated the results from analysis of transcription factor-binding motifs, the promoters and the SNP sites for each gene. Since epigenetic alterations also play an important role in lung carcinogenesis, genes with epigenetic regulation were also included. We hope HLungDB will enrich our knowledge about lung cancer biology and eventually lead to the development of novel therapeutic strategies. HLungDB can be freely accessed at http://www.megabionet.org/bio/hlung. |
| Title |
HLungDB: an integrated database of human lung cancer research |
| Short Title |
HLungDB |
| Date Added |
2009-12-30 09:26 |
| Date Modified |
2009-12-30 09:26 |